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HLA Ligand Atlas
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Warning The HLA Ligand Atlas is currently in a beta test phase. Please notice that the data and interface design might undergo frequent changes. You are welcome to contact us at and send us feedback or feature requests!


Class I Peptides


Class II Peptides




The HLA Ligand Atlas. A resource of natural HLA ligands presented on benign tissues.
Ana Marcu, Leon Bichmann, Leon Kuchenbecker, Linus Backert, Daniel J. Kowalewski, Lena Katharina Freudenmann, Markus W. Löffler, Maren Lübke, Juliane S. Walz, Julia Velz, Holger Moch, Luca Regli, Manuela Silginer, Michael Weller, Andreas Schlosser, Oliver Kohlbacher, Stefan Stevanović, Hans-Georg Rammensee, Marian C. Neidert bioRxiv 778944; doi: https://doi.org/10.1101/778944.
The HLA Ligand Atlas is a comprehensive collection of tissue and HLA allele specific HLA ligands that are naturally presented. The data was generated in standardized mass spectrometry experiments and analyzed using a well defined computational analysis workflow.
We provide an easy to use query interface to quickly identify peptides of interest in the database, e.g. using sequence patterns or by specifying a tissue or HLA allele of interest. Query results can be exported and the complete HLA Ligand Atlas can be downloaded.
  • Interface Release 0.9.13 2019-09-21

    Search page improvements, added Uniprot ID bulk search.

  • Interface Release 0.9.12 & Data Release 2019.09a 2019-09-18

    Improved data export column names. Fixed replicate binding filter.

  • Interface Release 0.9.11 2019-09-16

    Visual improvements and bug fixes

  • Data Release 2019.09 2019-09-10

    Initial beta data release

  • Interface Release 0.9.4 2019-09-10

    Initial beta interface release